ODL Diabetic Retinopathy
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ODL Diabetic Retinopathy

Oxford Medicine Online
 

Chapter 4 Diabetes and the eye

Paul M Dodson

  • • Diabetes mellitus is still one of the commonest causes of blindness worldwide.
  • • The ophthalmic complications of diabetes include diabetic retinopathy, cataracts, primary open angle and neovascular glaucoma, and cranial nerve palsies.
  • • Retinovascular disease including retinal vein and artery occlusion and non-arteritic ischaemic optic neuropathy are more common in diabetic subjects.
  • • Diabetic retinopathy occurs in approximately 40% of diabetic subjects, with ethnic differences.
  • • The primary abnormalities of diabetic retinopathy are capillary basement membrane thickening, such that it becomes porous, and capillary occlusion with resultant retinal ischaemia.
  • • In type 1 diabetes diabetic retinopathy is almost invariable after 15 years of disease duration. In type 2 diabetes 20% have retinal signs at diagnosis of diabetes, rising to a prevalence of 60% after 15 years of known disease duration.
  • • Major modifiable risk factors for diabetic retinopathy include poor glucose and blood pressure control and increasing lipid levels.






DOI: 10.1093/med/9780199544967.003.0004

Each section is written by a specialist with a specific role in a diabetic retinopathy screening scheme. This online reference is presented in full colour and contains over 100 images.

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